New publication: Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models

Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. Accepted, Human Molecular Genetics.

Chen Liang1,2, Qiang Shao1, Wei Zhang1, Mei Yang1, Qing Chang1, Rong Chen3, and Jian-Fu Chen1,*

  1. Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA 90033
  2. Department of Cellular Biology, University of Georgia, Athens, GA, 30602
  3. Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 100 N. Greene Street, Baltimore,MD 21205, USA