Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models. Accepted, Human Molecular Genetics.
Chen Liang1,2, Qiang Shao1, Wei Zhang1, Mei Yang1, Qing Chang1, Rong Chen3, and Jian-Fu Chen1,*
- Center for Craniofacial Molecular Biology, University of Southern California (USC), Los Angeles, CA 90033
- Department of Cellular Biology, University of Georgia, Athens, GA, 30602
- Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 100 N. Greene Street, Baltimore,MD 21205, USA